Mometasone furoate 0.1% w/w
Maxmom cream contains Mometasone furoate. It is a corticosteroid used topically for inflammation of the skin.
- Skin allergic reaction
- Eczema ( patches on the skin which becomes inflamed which causes itching and bleeding)
- Psoriasis ( red itchy scaly patches)
To be applied once daily not more than three weeks.
Mechanism of action
After local application of the drug, it gets absorbed from the surface of the skin and have high affinity to cytoplasmic receptor. The drug produces its action by interfering with the release of leukocytic acid hydrolases and prevent the inflamed cell not be accumulated with macrophages.
The drug after local application rarely gets absorbed by the skin.
The drug after application binds to plasma protein up to 98-99%. The metabolism of the drug is through hepatic CYP3A4 isoenzyme.
The excretion of the drug is through feces and urine.
- Hypersensitivity to any of the corticosteroid
- In viral infection of skin
- Patients with chronic disorders like diabetes mellitus, thyroid disease, heart failure etc
- In patients with seizure disorders
- In pregnant and lactating patients
- Hepatic and renal failure