NAZOTRA DUSTING POWDER 75GM

Packing

75 gm

Composition

Itraconazole    1%w/w

Description

One of the triazole antifungal agents that inhibits cytochrome P-450-dependent enzymes resulting in impairment of ergosterol synthesis. It has been used against histoplasmosis, blastomycosis, cryptococcal meningitis & aspergillosis.  Dusting Powder is a broad spectrum antifungal medicine used to treat skin infections such as athlete’s foot, jock itch and ringworm. It also relieves symptoms such as burning, itching, cracking of the skin and discomfort caused by these infections.

Indications

  • Nazotra Dusting Powder is used in the treatment of fungal skin infections
  • It is used to treat fungal infections of the mouth or vagina (thrush)
  • skin infections such as athlete’s foot, jock itch and ringworm
  • Infections in finger and toenails.

Dosage

Spread on affected area twice a day

Mechanism of Action

It is used to treat infections caused by fungi. Itraconazole works by preventing fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes

Pharmacology

Itraconazole, can inhibit P-glycoproteins causing drug-drug interactions by reducing elimination and increasing absorption of organic cation drugs. With conventional Itraconazole preparations serum levels can vary greatly between patients, often resulting in serum concentrations lower than the therapeutic index.For oral dose  It has therefore been conventionally advised that patients take itraconazole after a fatty meal rather than prior to eating.

Contraindications

Precaution

Allergic reactions to medications, food and preservatives

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