Sterk S6 Ointment


Clobetasol propionate                        0.05% w/w

Salicylic acid                                       6% w/w


Sterk- S6 ointment contains Clobetasol propionate and Salicylic acid. Clobetasol propionate is a corticosteroid of glucocorticoid class. It is used for the management of skin related disorders which includes eczema or psoriasis. It is the most potent glucocorticoid. Salicylic acid is a type of phenolic acid used to remove the outer layer of the skin. It is  a potent keratolytic agent.



  • Reduces the skin itching and redness
  • Skin inflammation
  • Severe bacterial infection



Twice daily for a period of 3-4 weeks


Mechanism of action

Clobetasol propionate

It produces inflammatory action by acting on induction of phospholipase A2 inhibitory protein which is called as lipocortins. These proteins produce control over biosynthesis of mediators of inflammation i.e PGs and leukotrienes. This causes inhibition of arachidonic acid. Clobetasol binds to glucocorticoid receptor which complexes, enters the nucleus of cell and modifies genetic transcription.



Salicylic acid

It produce its anti-inflammatory action by suppressing the enzyme responsible for producing inflammatory mediators which causes inflammation.



Clobetasol propionate


After topical application it is well absorbed by the skin. The absorption of the drug depends on the vehicle used in formulation of ointment.


It is well distributed and metabolized by the liver.


The excretion of the drug is through kidney; its metabolites are also excreted in bile.

Salicylic acid


After topical application the drug is well absorbed by the skin


About 50-80% of the drug is bound to plasma protein


The drug is excreted through urine




  • Patients with impaired circulation in  the blood




  • Not to be used on broken skin
  • Sensitivity test should be done if using it first time
  • Regular monitoring for any toxicity